S.NOCountryIndicationScientific LiteratureYear of publicationForm of Chitosan-based productType of studyStudy model
01Saudi ArabiaBurns Chitosan topical gel formulation in the management of burn wounds
2009Gel / HydrogelResearch PublicationAnimal
02USBurns Chitosan Acetate Bandage as a Topical Antimicrobial Dressing for Infected Burns
2009Wound DressingResearch PublicationAnimal
03BrazilBurns Improvement of dermal burn healing by combining sodium alginate/chitosan-based films and low level laser therapy
2011FilmsResearch PublicationAnimal
04ChinaBurns Hydrogel sheets of chitosan, honey and gelatin as burn wound dressings
2012Gel / HydrogelResearch PublicationAnimal
05AlgeriaBurns Evaluation of healing activity of PVA/chitosan hydrogels on deep second degree burn: pharmacological and toxicological tests
2013Gel/HydrogelResearch PublicationAnimal
06BrazilBurns Microparticles of Aloe vera/vitamin E/chitosan: Microscopic, a nuclear imaging and an in vivo test analysis for burn treatment2014Other / MultipleResearch PublicationAnimal
07TaiwanGeneral Wounds Assessment of reinforced poly(ethylene glycol) chitosan hydrogels as dressings in a mouse skin wound defect model
2013Gel/HydrogelResearch PublicationAnimal
08TurkeyBurnsChitosan gel formulations containing egg yolk oil and epidermal growth factor for dermal burn treatment2015Gel/HydrogelResearch PublicationAnimal
09ChinaSpinal Cord injury NT3-chitosan elicits robust endogenous neurogenesis to enable functional recovery after spinal cord injury
2015Other / MultipleResearch PublicationAnimal
10IranUlcers Potential application of nanochitosan film as a therapeutic agent against cutaneous leishmaniasis caused by L. major
2015FilmsResearch PublicationAnimal
11IranUlcers Chitosan gel-embedded moxifloxacin niosomes: An efficient antimicrobial hybrid system for burn infection2016Gel / HydrogelResearch PublicationAnimal
12ChinaBurns On-Demand Dissolvable Self-Healing Hydrogel Based on Carboxymethyl Chitosan and Cellulose Nanocrystal for Deep Partial Thickness Burn Wound Healing2018Gel / HydrogelResearch PublicationAnimal
13IranBurns Bromelain-loaded chitosan nanofibers prepared by electrospinning method for burn wound healing in animal models2019Other / MultipleResearch PublicationAnimal
14PakistanGeneral WoundsSilver nanoparticle impregnated chitosan-PEG hydrogel enhances wound healing in diabetes induced rabbits2019Gel / HydrogelResearch PublicationAnimal
15ChinaOthers (Endometrial Injury)Controlled releasing of SDF-1α in chitosan-heparin hydrogel for endometrium injury healing in rat model2020Gel / HydrogelResearch PublicationAnimal
16IranBurnsEfficacy of topical platelet-rich plasma and chitosan co-administration on Candida albicans-infected partial thickness burn wound healing2020Gel / HydrogelResearch PublicationAnimal
17IranGeneral WoundsWound healing with alginate/chitosan hydrogel containing hesperidin in rat model2020Gel / HydrogelResearch PublicationAnimal
18BrazilUlcersA new waterborne chitosan-based polyurethane hydrogel as a vehicle to transplant bone marrow mesenchymal cells improved wound healing of ulcers in a diabetic rat model2020MembranesResearch PublicationAnimal
19BrazilBurnsCarboxymethyl chitosan hydrogel formulations enhance the healing process in experimental partial-thickness (second-degree) burn wound healing2021Gel / HydrogelResearch PublicationAnimal
19BrazilBurnsCarboxymethyl chitosan hydrogel formulations enhance the healing process in experimental partial-thickness (second-degree) burn wound healing2021Gel / HydrogelResearch PublicationAnimal
20ChinaOthers (Multiple Wounds)Effects of chitosan-collagen dressing on wound healing in vitro and in vivo assays2021Wound DressingResearch PublicationAnimal
21ChinaBurnsChitosan degradation products promote healing of burn wounds of rat skin2022Other / MultipleResearch PublicationAnimal
22ChinaSpinal Cord injuryChronic spinal cord injury repair by NT3-chitosan only occurs after clearance of the lesion scar2022Gel / HydrogelResearch PublicationAnimal
23ChileOthers (Multiple Wounds)Chitosan composite films. Biomedical applications2008FilmsResearch PublicationHuman
24IranBurnsThe effect of chitosan-based gel on second degree burn wounds2016Gel / HydrogelResearch PublicationHuman
25IndiaTraumatic WoundsAssessing the Efficacy of Haemostatic Dressing Axiostat® In Trauma Care at a Tertiary Care Hospital in India: A Comparison with Conventional Cotton Gauze2016Wound DressingResearch PublicationHuman
26USBurnsThe use of a chitosan dressing with silver in the management of paediatric burn wounds: a pilot study2017Wound DressingResearch PublicationHuman
27MalaysiaTraumatic WoundsEfficacy of chitosan derivative films versus hydrocolloid dressing on superficial wounds2018FilmsResearch PublicationHuman
28MalaysiaUlcersNano-colloidal silver and chitosan bioactive wound dressings in managing diabetic foot ulcers: case series2018Gel / HydrogelResearch PublicationHuman
29MexicoUlcersChitosan treatment for skin ulcers associated with diabetes2018FilmsResearch PublicationHuman
30MexicoUlcers Efficacy and safety of the combination of isosorbide dinitrate spray and chitosan gel for the treatment of diabetic foot ulcers: A double-blind, randomized, clinical trial2018Gel / HydrogelResearch PublicationHuman
31IranUlcersChitosan‑based biocompatible dressing for treatment of recalcitrant lesions of cutaneous leishmaniasis: A pilot clinical study2019FilmsResearch PublicationHuman
32MexicoUlcersCharacterization and efficacy of chitosan membranes in the treatment of skin ulcers2019MembranesResearch PublicationHuman
33SpainOthers (Dental Inflammation)Characterization and efficacy of chitosan membranes in the treatment of skin ulcers2020Gel / HydrogelResearch PublicationHuman
34ChinaBurnsStudy on scar repair and wound nursing of chitosan-based composite electrospun nanofibers in first aid of burn2021Other / MultipleResearch PublicationHuman
35ThailandOthers (Skin Sebum)The Efficacy and Safety of Chitosan on Facial Skin Sebum2021Gel / HydrogelResearch PublicationHuman
36ChinaBurnsApplication and clinical efficacy of Sufu medical chitosan hydrogel dressing in radiation skin damage caused by radiotherapy for cervical cancer2022Gel / HydrogelResearch PublicationHuman
37ChinaOthers (Chronic refractory wounds)Clinical efficacy of chitosan-based hydrocolloid dressing in the treatment of chronic refractory wounds
2022Wound DressingResearch PublicationHuman
38IndiaUlcersUse of Chitosan-based Dressings for the Management of a Chronic Lower Limb Ulcer: A Case Report2022Wound DressingResearch PublicationHuman
39ChinaBurnsClinical efficacy of wet dressing combined with chitosan wound dressing in the treatment of deep second‐degree burn wounds: A prospective, randomised, single‐blind, positive control clinical trial2023Wound DressingResearch PublicationHuman
40MalaysiaGeneral WoundsA Prospective Multicenter Randomized Controlled Trial to Evaluate the Efficacy of Chitosan Hydrogel Paste in Comparison to Commercial Hydroactive Gel as a Wound Bed Preparation2023Gel / HydrogelResearch PublicationHuman
41IndiaOthers (Multiple Wounds)Drug loaded thermoresponsive and cytocompatible chitosan based hydrogel as a potential wound dressing2011Gel / HydrogelResearch PublicationIn vitro
42PortugalOthers (Multiple Wounds)Chitosan drives anti-inflammatory macrophage polarisation and pro-inflammatory dendritic cell stimulation2012Other / MultipleResearch PublicationIn vitro
43South KoreaOthers (Drug resistant bacteria)Antimicrobial Action of Water-Soluble β-Chitosan against Clinical Multi-Drug Resistant Bacteria2015Other / MultipleResearch PublicationIn vitro
44IndiaInfected WoundCefuroxime conjugated chitosan hydrogel for treatment of wound infections2019Gel / HydrogelResearch PublicationIn vitro
45PakistanOthers (Multiple Wounds)Stimuli responsive biopolymer (chitosan) based blend hydrogels for wound healing application2019Gel / HydrogelResearch PublicationIn vitro
46IndiaOthers (Multiple Wounds)Preparation and characterization of chitosan/pectin/ZnO porous films for wound healing2020FilmsResearch PublicationIn vitro
47IndiaOthers (Efficiency on L929 Fibroblast)Evaluation of curcumin-loaded chitosan nanoparticles for wound healing activity2023Other / MultipleResearch PublicationIn vitro
48USBurnsIBiomaterials based on chitin and chitosan in wound dressing applications2011Other / MultipleReview PublicationMixed
49IndiaOthers (Multiple Wounds)IBiomaterials based on chitin and chitosan in wound dressing applications2011Other / MultipleReview PublicationMixed
50South KoreaTraumatic WoundsIn Situ Forming and Rutin-Releasing Chitosan Hydrogels As Injectable Dressings for Dermal Wound Healing2011Gel / HydrogelReview PublicationMixed
51RomaniaOthers (Multiple Wounds)Chitosan as a starting material for wound healing applications2015Other / MultipleReview PublicationMixed
52IndiaOthers (Multiple Wounds)Chitosan Based Scaffolds and Their Applications in Wound Healing2016Other / MultipleReview PublicationMixed
53IndiaGeneral WoundsChitosan based metallic nanocomposite scaffolds as antimicrobial wound dressings2018ScaffoldReview PublicationMixed
54ChinaOthers (Multiple Wounds)A functional chitosan-based hydrogel as a wound dressing and drug delivery system in the treatment of wound healing
2018Gel / HydrogelReview PublicationMixed
55IranGeneral Woundshttp://Chitosan/alginate hydrogels containing Alpha-tocopherol for wound healing in rat model2019Gel / HydrogelReview PublicationMixed
56ChinaInfected WoundInjectable hydrogel composed of hydrophobically modified chitosan/oxidized-dextran for wound healing2019Gel / HydrogelResearch PublicationMixed
57IndiaChitosan and gelatin-based electrospun fibers for bone tissue engineering2019ScaffoldResearch PublicationMixed
58EgyptOthers (Multiple Wounds)Soft hydrogel based on modified chitosan containing P. granatum peel extract and its nano-forms: Multiparticulate study on chronic wounds treatment2019Gel / HydrogelReview PublicationMixed
59ChinaTraumatic WoundsEnhanced cutaneous wound healing by functional injectable thermo-sensitive chitosan-based hydrogel encapsulated human umbilical cord-mesenchymal stem cells2019Gel / HydrogelResearch PublicationMixed
60ChinaTraumatic WoundsQuaternized chitosan-Matrigel-polyacrylamide hydrogels as wound dressing for wound repair and regeneration2019Gel / HydrogelResearch PublicationMixed
61ChinaTraumatic WoundsQuaternized chitosan-Matrigel-polyacrylamide hydrogels as wound dressing for wound repair and regeneration2019Research PublicationMixedMixed
62ChinaGeneral WoundsModulating cationicity of chitosan hydrogel to prevent hypertrophic scar formation during wound healing2020Gel / HydrogelResearch PublicationMixed
63South AfricaOthers (Multiple Wounds)Chitosan and Cellulose-Based Hydrogels
for Wound Management
2020Gel / HydrogelReview PublicationMixed
64RomaniaInfected WoundPreparation and Antimicrobial Activity of Chitosan and Its Derivatives: A Concise Review2021Other / MultipleReview PublicationMixed
65ChinaOthers (Multiple Wounds)Chitosan-Based Functional Materials for Skin Wound Repair: Mechanisms and Applications2021Gel / HydrogelReview PublicationMixed
66IndiaOthers (Progressive Wounds)Chitosan/Hyaluronic acid/Alginate and an assorted polymers loaded with honey, plant, and marine compounds for progressive wound healing-Know-how2021Other / MultipleReview PublicationMixed
67MexicoBurnsThe use of chitosan as a skin-regeneration agent in burns injuries: A review2022Other / MultipleReview PublicationMixed
68NigeriaOthers (Multiple Wounds) A short review on chitosan and gelatin-based hydrogel composite polymers for wound healing
2022Gel / HydrogelReview PublicationMixed